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HGH And Amino Acids Such As GH Secretagogues

Arginine Amino Acid

A review of the literature maintains that combining growth hormone amino acids such as GH secretagogues with growth hormone injections can be beneficial to relieving the symptoms caused by a GH deficiency. Secretagogues agents are growth hormone releasing compounds. They help the body to naturally produce growth hormone on its own by stimulating the pituitary gland (where growth hormone is primarily produced).

Most sources agree that on their own, amino acid supplements will not give substantial benefits. However, combining secretagogues with human growth hormone subcutaneous injections can be highly effective.

Many experts advocate for using amino acids to boost growth hormone production, but only along with properly prescribed HGH injections. Some of the GH secretagogues amino acids that are popular and used often are:

Glutamine Amino Acid

  • Ornithine
  • Arginine
  • L-Dopa
  • Ornithine-alpha-ketoglutarate (OKG)
  • Arginine Pyroglutamate and Lysine
  • Glycine
  • Glutamine
  • GABA

All these supplements have been studied and tested. Claims have been made that they can increase the production of growth hormone naturally within the body when added as a supplement. When HGH and amino acid secretagogues are combined simultaneously for treatment, results have been very positive.

Literature Regarding HGH And Amino Acid Secretagogues

When a person is dealing with a growth hormone deficiency, the best course of treatment is to replace the missing hormones with injectable HGH while also stimulating the pituitary gland to produce GH on its own, according to the National Institutes of Health. With a supplementation of a GH releasing hormone or what is also called a GH secretagogue could be the best option.

Studies have confirmed that combining HGH and amino acid secretagogue can give faster and stronger benefits such as increased:

  • muscle mass
  • strength
  • sexual drive
  • erection frequency
  • exercise capacity
  • strength of bones
  • stamina
  • endurance

An article published in Clinical Interventions in Aging was reviewed by some of the most influential academics from Duke University, the University of Virginia and the University of Washington. The study was based on proving that hormone replacement therapy for an adult GH deficiency can improve strength, movement, aerobic capacity, cardiovascular issues and body composition by decreasing excess weight.

The study aimed at confirming that by replacing GH with HGH injections and stimulating GH to produce naturally with GH releasing hormone or a GH secretagogue, this can strengthen a person’s physical and mental capacities. It can also help them to live a longer life in an independent fashion.

The conclusion of the study was positive with significant results. The combination of HGH injections and amino acid secretagogues made beneficial changes to body composition and physical functioning. It helped to ease subjects into the normal aging process with the common symptoms that go along with the process. The study suggested further research on this topic.

The Future Of HGH And Amino Acid Secretagogue

Many pharmaceutical companies are working hard to continue researching the effectiveness of HGH secretagogues amino acids. They want to find better ways to help the body naturally release growth hormone from the pituitary gland when it is resting dormant in the brain.

Many researchers and physicians in this innovative field of medicine believe that natural secretagogues amino acids very closely replicate the body’s naturally produced growth hormone. They believe that hormone therapy using subcutaneous injections of HGH secretagogues is the best way to increase the body’s growth hormone levels for overall optimal health.

Medically reviewed by   Reviewers National HRT Staff - Updated on July 3, 2019

Please note that the information provided in this article is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment.


  1. Use of amino acids as growth hormone-releasing agents by athletes.Chromiak JA, Antonio J.Nutrition. 2002 Jul-Aug;18(7-8):657-6
  2. Growth hormone (GH)–releasing hormone and GH secretagogues in normal aging: Fountain of Youth or Pool of Tantalus? Natural and Synthetic Growth Hormone Secretagogues Giovanna Motta Stefano Allasia Marco Zavattaro Ezio Ghigo Fabio Lanfranco Encyclopedia of Endocrine Diseases (Second Edition)
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  4. Clinical Obstetrics and Gynecology
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