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Treatment for Low Growth Hormone

Written by Author - Authors Medical experts of the National HRT Clinic - November 4, 2015

If you’ve been diagnosed with low growth hormone, treatment can transform how you feel and look. Whether it’s the fatigue that won’t lift, the weight that won’t shift, or the general sense that your body isn’t working like it used to, HGH treatment addresses the root cause. There are several treatment options available, from HGH injections to secretagogue therapy to lifestyle modifications. This guide explains your options and how to get started.

Treatment of Low HGH

Treatment Starts with Diagnosis

Before any treatment begins, you need a proper diagnosis. This means:

  • Medical evaluation: A doctor reviews your symptoms, medical history, and current medications. This ensures HGH treatment is safe for you and identifies any conditions that would make it inadvisable.
  • Blood testing: IGF-1 testing (and possibly other hormone panels) confirms that your growth hormone is actually low. This is essential—treatment only makes sense if your growth hormone is genuinely deficient.
  • Assessment of symptoms: Your doctor correlates your low IGF-1 with your symptoms. Someone with low IGF-1 but no symptoms might not need treatment. Someone with low IGF-1 and multiple symptoms affecting quality of life is a clear candidate for therapy.

Once diagnosis is confirmed, our doctor discusses treatment options and helps you choose the approach that’s best for your situation.

HGH Injection Therapy

HGH injections are the most common and most effective treatment for low growth hormone. They involve injecting synthetic human growth hormone subcutaneously (under the skin) daily or as prescribed by your doctor.

How it works: HGH injections deliver bioidentical growth hormone directly into your bloodstream, triggering IGF-1 production that builds muscle, burns fat, improves sleep, and strengthens bones. Several FDA-approved brands are available, and our doctor recommends the one that fits your needs.

Effectiveness: When dosed appropriately and monitored properly, HGH therapy produces excellent results in most patients. Improvements typically begin within 4-6 weeks, with full benefits unfolding over 6-12 months. For a detailed results timeline, see our guide on HGH therapy results.

Secretagogue Therapy (Sermorelin)

Secretagogues are medications that stimulate your own pituitary gland to produce and release more growth hormone naturally. They don’t provide synthetic HGH directly—instead, they encourage your body to make more of its own.

Sermorelin is the most common secretagogue used. It’s a peptide that signals your pituitary to release growth hormone naturally. It costs less than HGH injections and works best for people with mild to moderate deficiency who want a gentler approach. Results take 2-3 months to become noticeable. For a full comparison of sermorelin vs. HGH, see our sermorelin therapy guide.

Lifestyle Changes That Support GH Production

While medication is often necessary for significant growth hormone deficiency, lifestyle factors also influence GH production. These should be part of any treatment plan:

  • Sleep optimization: Growth hormone is released primarily during deep sleep. Improving sleep quality through good sleep hygiene (consistent bedtime, dark cool room, no screens before bed) can naturally increase GH production. This is why your doctor will ask about your sleep.
  • Regular exercise: Resistance training and high-intensity interval training (HIIT) stimulate growth hormone release. Regular exercise, especially strength training, supports and maximizes the benefits of HGH therapy.
  • Stress reduction: Chronic stress suppresses growth hormone. Meditation, yoga, breathing exercises, and stress management support healthy GH levels.
  • Nutrition: Adequate protein intake, avoiding extreme calorie restriction, and balanced nutrition support hormone production and HGH therapy effectiveness.
  • Weight management: Obesity suppresses growth hormone. If you’re overweight, weight loss (supported by HGH therapy if needed) helps restore healthier GH levels.
  • Limit alcohol: Excessive alcohol consumption suppresses growth hormone. Moderate or no alcohol intake supports HGH therapy.

These lifestyle factors alone rarely restore growth hormone to normal in people with significant deficiency, but they’re essential components of any treatment approach.

What to Expect During Treatment

Results from HGH therapy unfold gradually. Most people notice sleep and energy improvements within the first few weeks, visible body composition and skin changes by months 3-4, and full benefits by 6-12 months. Your doctor monitors your progress with regular blood work and adjusts your dose as needed.

For a detailed month-by-month timeline of what to expect, see our guide on HGH therapy results.

Getting Started

Treatment begins with a consultation with a National HRT doctor, followed by blood work at a partner laboratory near you, diagnosis, and—if you qualify—a prescription sent directly to a licensed pharmacy. FDA-approved medication is shipped to your home within 1-2 weeks of your initial consultation.

For a detailed walkthrough of each step, see our guide on how to get an HGH prescription.

FAQs

Can low HGH be treated without injections?

HGH injections are the most effective treatment, but other options exist. Sermorelin therapy stimulates your body to produce more of its own growth hormone. Lifestyle changes—better sleep, exercise, stress reduction, nutrition—support natural GH production. However, these alternatives are typically less effective than direct HGH injection therapy. Your doctor will recommend the approach most appropriate for your specific situation.

How long does HGH treatment take?

This depends on what you mean by “take.” First improvements in energy and sleep often appear within 4-6 weeks. Noticeable body composition changes and skin improvements typically appear by 3-4 months. Full results take about 6-12 months. Most people continue HGH therapy long-term to maintain results—stopping treatment allows growth hormone levels to decline again over time.

Is sermorelin as effective as HGH injections?

Sermorelin is less potent than direct HGH injection therapy, but it’s effective for mild to moderate low growth hormone. Sermorelin stimulates your body to produce more of its own GH, while HGH injections directly provide synthetic growth hormone. For significant GH deficiency, HGH injections are usually more effective. For mild deficiency or those preferring a gentler approach, sermorelin can work well. Our doctor recommends which is best for you.

Can lifestyle changes fix low HGH?

Lifestyle changes (better sleep, exercise, stress reduction, good nutrition) can modestly increase natural GH production and are important components of treatment. However, they cannot fully restore growth hormone in someone with significant deficiency due to aging or pituitary disease. Lifestyle changes should be combined with medication (HGH or sermorelin) for people with documented low growth hormone. Think of lifestyle changes as supporting but not replacing medical treatment.


Medical Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or changing any hormone therapy or medication. Individual results vary, and treatment decisions should be made between you and your doctor based on your specific medical history and needs.


Medically reviewed by   Reviewers National HRT Staff - Updated on May 4, 2026

Please note that the information provided in this article is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment.