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What Is the Link Between Testosterone and Growth Hormone?

Written by Author - Authors Medical experts of the National HRT Clinic - November 20, 2020


Both testosterone and human growth hormone (HGH) are critically important to your health and well-being. But what else do these two essential hormones have in common?

HGH and testosterone have what is known as a synergistic effect. That means the biological effects of one, enhances those of the other. Both testosterone and growth hormone are essential for:

  • Muscle growth
  • Bone health
  • Fat metabolism and the energy levels
  • Regulated sleep
  • Sexual health
  • Mental acuity

But, the most important thing that growth hormone and testosterone have in common, is that the levels of each in your blood drop as you age. This means that most men and women, between the ages of 45 and 65, are suffering from some degree of either growth hormone deficiency, testosterone deficiency, or in many cases both!

Growth hormone and testosterone are both vital to your overall health and well-being.

Are Testosterone and HGH Similiar?

Growth hormone and testosterone are both very important hormones, however they are not the same thing.

Testosterone is a male or sex hormone, belonging to the class of hormones known as “androgens.” Growth hormone is a protein made and secreted by the pituitary gland.

However, they are both known as “anabolic hormones.” The word anabolic in medical terms simply means something that stimulates the growth of cells and tissues. Both human growth hormone and testosterone stimulate and regulate all the processes that allow a boy to grow into a man. As such, both HGH and testosterone levels are extremely high in children and in adolescents.


However, once you hit your 20s, the levels of HGH and testosterone in your blood peak. After that they start a steady decline.

Both HGH and testosterone work in harmony to provide strength, vitality, and peak performance at any age. Without adequate amounts of either of these two hormones, your body would never be able to burn fat, or build muscle.

Unfortunately, your levels of both growth hormone and HGH decline as you age. There is also another thing these two hormones have in common. The symptoms of both low testosterone and age-related growth hormone deficiency are practically the same. In fact, studies have shown that, a decrease in human growth hormone may spark a decrease in testosterone levels and vice versa.

However, the good news is something else that both HGH and testosterone have in common. Patients suffering from low levels of either, or both, can benefit from hormone replacement therapy!

Both your testosterone levels and your HGH levels decline as you age.

What Are the Benefits of Testosterone Therapy?


For men or women suffering from age-related testosterone deficiency the benefits of testosterone replacement therapy are many. One of the first benefits of testosterone therapy that men notice is an improvement in their sex lives.

There are many ways beyond sexual performance that testosterone therapy can help improve your quality of life. Many men say that testosterone therapy has given them “their edge back.” Besides feeling physically stronger, and more fit, much of that feeling of renewed power comes from the fact that testosterone therapy also improves mood, focus, and concentration. In addition to increasing the libido, and having a positive impact on cognition, testosterone therapy also:

  • Encourages heart health
  • Helps prevent osteoporosis by improving bone density
  • Fights fat
  • Increases muscle strength
  • Improves mood
  • Improves sleep

What Are the Benefits of Growth Hormone Therapy?


Similarly, men or women feeling the effects of declining HGH levels as they age, can benefit greatly from growth hormone therapy. Some of the many benefits of growth hormone injections include:

  • Increased strength
  • Increased stamina
  • More energy
  • Improved sexual function
  • Improved memory and cognition
  • Better sleep
  • Better moods
  • Increased ability to burn fat and build muscle
  • Healthier skin and bones

What Are the Benefits of Combining Testosterone and HGH Replacement?

benefits-of-combining-testosterone-and-hgh-replacementHave you heard the expression “two are better than one?” That is often the case when it comes to hormone replacement therapy.

When patients comes to us suffering from low testosterone, they almost always are suffering from age-related growth hormone deficiency as well. The reverse is also often true.

This is why many of our patients benefit from combining HGH replacement with testosterone therapy. If you look at the overall benefits of both hormone replacement therapies, you will find that they produce some very positive effects on your health and vitality.
In addition, recent research has shown that use of both hormones simultaneously, increases muscle mass and decreases body fat, more than just using one of the hormones alone.

The surest, safest, and most effective way to boost your levels of growth hormone and testosterone is via hormone replacement therapy. However, there are some ways that you may be able to naturally boost your levels of these critical hormones. You can increase your HGH and testosterone levels by:

  • Exercise, particularly high intensity workouts
  • Getting enough sleep
  • Taking amino acid supplements
  • Intermittent fasting
  • Reducing your sugar intake
  • Reducing your alcohol consumption

The bottom line is, if you are no longer feeling like the man or woman you once were, or would like to be, you may benefit from growth hormone therapy, and or testosterone therapy. But, the only way to know for sure is to come see us, and have your hormone levels tested.

Testosterone replacement therapy and growth hormone therapy can be used together to treat low testosterone, and/or age-related growth hormone decline.

Now that you know a little bit more about how testosterone and growth hormone are related, why not contact us, and find out more about the many life changing benefits of testosterone and/or growth hormone replacement therapy.

Medically reviewed by   Reviewers National HRT Staff - Updated on November 21, 2023

Please note that the information provided in this article is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment.