2475 Mercer Avenue, Suite 101
West Palm Beach, FL 33401
Get FREE Consultation

Should Testosterone and HCG Be Taken Together?

Written by Author - Authors Medical experts of the National HRT Clinic - November 23, 2015

The condition known asLow T in men can have a damaging effect on the ability to father a child, maintain a healthy body, and keep a sharp mind. The automatic assumption of many males is that testosterone is all that is needed to reverse this problem, but that is not always the case. Human Chorionic Gonadotropin also aids in the stimulation of testosterone production, which is why it is typically prescribed as an adjunct part of Low T therapy.

Combining testosterone with HCG provides a male with what he needs to function properly. One of the biggest problems seen in men who use testosterone replacement therapy without HCG is that their testicles often shrink in size. What is happening here is that the body experiences an increase in testosterone and the brain then believes that there is enough testosterone present, so it does not send the LH signals necessary to stimulate further production of this essential chemical messenger.

Without HCG, testosterone production will not be stimulated in the testes because the brain would not be sending luteinizing hormone signals to commence this secretion. HCG quickly restores the testicles back to their proper size and function.

What Does HCG Do with Testosterone?

The function of LH – luteinizing hormone – is mimicked by HCG, and testosterone production is then increased as the Leydig cells in the testes are stimulated to return to normal size and function. In other words, HCG takes on the role of LH during the course of testosterone treatment.

HCG should not be used for long-term treatment in men with Low T, as it will start to desensitize the Leydig cells to naturally produced LH. It is essential that the testicles be able to recognize luteinizing hormone supplied by the brain to increase testosterone production and not rely on HCG for extended periods of time.

How Does HCG Influence Other Hormones?

When using HCG for testosterone production and secretion, one of the aspects of this will be an increase of estrogen in the body. Although males do require a certain amount of estrogen, the excess testosterone will increase the conversion process. For this reason, anastrozole may be provided to stop the aromatization process converting the excess testosterone into estrogen in order to maintain a proper ratio.

Another benefit of taking testosterone and HCG together is that cholesterol can increase with treatment for Low T. Cholesterol is the source of the chemical structure for many of the hormones made in the body. The process of changing cholesterol into hormones begins with an enzyme that is stimulated by LH, which is suppressed when on testosterone treatment unless HCG is used. HCG injections help to stimulate the process so that everything proceeds as required.

How to Take HCG with Testosterone

HCG and Testosterone Doctor

Taking testosterone and HCG together means following a specific protocol as prescribed by the doctor. For some men, this might mean using HCG for one week and then going three weeks before using it again. Others may not use it until the end of their cycle. It is essential to follow the direction of the doctor at all times.

HCG comes as a freeze-dried powder that will need to be reconstituted with the bacteriostatic water that will be included in the testosterone treatment kit. Since the HCG molecule is a fragile peptide, take great care not to shake the vial while mixing. Only gentle swirling is necessary.

HCG is injected into the subcutaneous fat in the lower abdomen and must be refrigerated when not being used once it has been mixed.

Where to Get Testosterone and HCG

Determining the best way to purchase a course of testosterone HCG treatment is essential to a positive outcome. This means avoiding websites that offer to sell these medications without a doctor’s prescription. There are too many risks involved with purchasing pharmaceutical products in this way, including:

  • Fraudulent companies
  • Confiscation during shipment due to buying medication illegally without a prescription
  • Expired products
  • Toxic ingredients – rat poison, drywall, cement
  • Bacterial residue left over from manufacturing
  • Diluted products
  • Drug substitutions
  • False labels
  • Wrong dosages or strengths

Hormone replacement therapy such as testosterone and HCG require blood testing before they can be prescribed. This helps the doctor ascertain what type of treatment is required and in what dosage for desired results.

It is best to turn to a hormone replacement specialist in the United States for the necessary diagnostic testing and treatment. That is how to ensure that the proper treatment is being prescribed and that all pharmaceuticals are sent from a licensed US pharmacy.

National HRT is here to help men and women conquer the symptoms of hormonal deficiency or imbalance. We offer nationwide testing and diagnostic services, along with the finest level of customer care and service. Affordable treatment options are available.

Medically reviewed by   Reviewers National HRT Staff - Updated on November 21, 2023

Please note that the information provided in this article is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment.


  1. Healio
  2. PPM
  3. The Use of HCG-Based Combination Therapy for Recovery of Spermatogenesis after Testosterone Use Evan P. Wenker, BS , James M. Dupree, MD, Gavin M. Langille, MD, Jason Kovac, MD, Ranjith Ramasamy, MD, Dolores Lamb, Ph.D., Jesse N. Mills, MD ,Larry I. Lipshultz, MD,’Correspondence information about the author MD Larry I. LipshultzEmail the author MD Larry I. Lipshultz PlumX Metrics June 2015Volume 12, Issue 6, Pages 1334–1337
  4. Livestrong
Louis Juarz

Hello, I'm starting testosterone treatment today. I've been in Gonadotropin for 2 years but my level of testosterone is pretty low. I feel tired my libido is really low and some other problems. Before this treatment I was using testosterone for over 5 years this caused shrinkage of my testicles. However my Dr. who's a female Dr. Does not want to give me both medication. She thinks this websites don't know what you're talking about. Can you please advice me how to convince my Dr. and How do I inject both medication together since I have some bottles left of the chorionic. Thank you for your attention