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Humatrope vs. Norditropin: Choose the Best HGH for You

Written by Author - Authors Medical experts of the National HRT Clinic - August 24, 2016

Norditropin and Humatrope

Adults who are prescribed HGH therapy by their doctors to combat growth hormone deficiency have many choices for treatment. Choosing the best HGH product for your needs is going to be a personal decision that will be made during a discussion with your hormone replacement specialist.

A comparison between Humatrope vs. Norditropin turns up a few significant differences:

  1. The price of Humatrope is a little higher than Norditropin
  2. Norditropin comes to you already mixed in prefilled cartridges
  3. Humatrope needs reconstituting before use

One benefit for many people is that both Humatrope and Norditropin are manufactured right here in the USA. There is no risk of contamination from bacteria as in many of the lesser-known HGH products that are made in less than desirable conditions overseas in places such as China.

Both brands are of the highest quality and are made to exacting standards for the treatment of GH deficiency.

Some factors may influence a person towards one product or the other when deciding between Humatrope and Norditropin.

If keeping a medication refrigerated is going to be a problem, then Norditropin may be the better option. Working with a knowledgeable specialist will help make this decision easier in the long run.

Making the right choice for your personal needs will bring the best possible results. Here is a breakdown of what the two brands of HGH have to offer:

Humatrope HGH Options

Humatrope HGH Options

Humatrope HGH is manufactured by the pharmaceutical company Eli Lilly. Aside from being offered in the standard vial and syringe format that most people are used to seeing injectable medications provided as Humatrope is also available in an easier-to-use injector pen.

One of the differences comparing Humatrope vs. Norditropin is in how the cartridges for the injector pens are provided. Humatrope has cartridges that must first be reconstituted before use.

The procedure here is extremely simple as a diluent syringe that is prefilled with the exact amount of solution is provided for use.

Humatrope is available in current dosages:

  • HumatroPen 6 mg
  • HumatroPen 12 mg
  • HumatroPen 24 mg

The diluent syringe attaches to the Humatrope cartridge for quick and easy mixing. The reconstituted cartridge is then connected to the corresponding HumatroPen device for use. The reusable pen system is both long-lasting and economical. Humatrope must be kept refrigerated at all times.

Norditropin HGH Options

Norditropin HGH is manufactured by Novo Nordisk. Norditropin is available in a number of different ways besides the standard freeze-dried vial, including:

  • Norditropin FlexPro Pen 5 mg
  • Norditropin FlexPro Pen 10 mg
  • Norditropin FlexPro Pen 15 mg
  • NordiFlex Pen 30 mg

Does Norditropin need to be refrigerated?

The main benefit of Norditropin FlexPro is that it can be stored at room temperature for up to three weeks. This makes them an excellent choice for people who travel frequently and want the convenience of not having to keep their medication refrigerated all of the time.

Another benefit of the Norditropin Pen systems is that they all come premixed and prefilled. There is no reconstituting of the powdered medication, and there are no cartridges to replace. Each pen system is preloaded and ready for use.

How to choose the best HGH for your needs

Choosing the best HGH brand and injector style for your needs is going to be based on a number of different factors.

We have already discussed the refrigeration aspect of this process, as people who travel a great deal are often best served by a brand of HGH that does not require constant refrigeration.

Due to the delicate nature of HGH, if you do not expect to be traveling, then it is recommended to stick to a brand of HGH that does require refrigeration.

The next thing to discuss with the HRT specialist is the simplicity of handling the pen unit. Some HGH brands come with preset dosing amounts, which could inhibit the adjustment of the dosage by the doctor. Others have simple to turn knobs.

There are also different ways of using the pen systems to discuss, and you may find one system will be easier for you to use than another, especially if you are experiencing any arthritis or stiffness in your hands or fingers.

Price is also a factor for many people, and although we offer affordable options for the treatment of adult growth hormone deficiency, some brands are definitely more expensive than others.

Please feel free to ask our specialist any questions about both Humatrope and Norditropin, as well as any other brand of HGH injections. We will offer advice and suggestions for the best choice for your needs.

National HRT provides free and confidential consultations to adults throughout the US about hormone replacement therapy. We offer local diagnostic testing and superior service and care.

Medically reviewed by   Reviewers National HRT Staff - Updated on March 20, 2023

Please note that the information provided in this article is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment.


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  2. RxList
  3. User assessment of Norditropin NordiFlex®, a new prefilled growth hormone pen: a Phase IV multicenter prospective study
  4. A new pen device for injection of recombinant human growth hormone: a convenience, functionality and usability evaluation study Marietta Sauer and Carole Abbotts 2018; 12: 27–34.
  5. GoodRx